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What does UBO stand for?

UBO stands for upper-body-obese


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Net fat storage in the adipose tissue after a meal requires inhibition of lipolysis, achieved by increased circulating insulin levels. This mechanism is less effective both in men and in upper body obese women [117,118] compared to women with peripheral fat distribution. Differences in insulin sensitivity (higher in females) are reproduced in vitro in isolated adipocytes of pre- [119], but not post-menopausal women [120] and can also be causally linked to the detrimental postprandial metabolic profile seen in men and upper body obese women.
Fontbonne A, Diouf I, Baccara-Dinet M, Eschwege E, Charles A: Effects of 1-year treatment with metformin on metabolic and cardiovascular risk factors in non-diabetic upper-body obese subjects with mild glucose anomalies: a post-hoc analysis of the BIGPRO1 trial. Diabetes Metab 2009, 35:385-391. PubMed Abstract | Publisher Full Text.
Intra-abdominal pressure is higher in obese patients [86], what may also impact on adipocyte stability. Preadipocytes of upper-body obese women exhibit reduced differentiation and are more prone to apoptosis than preadipocytes isolated from adipose tissue of lower-body obese or lean women [87]. The factors involved in this preadipocyte behaviour deserve investigation [88]. Moreover, it has been proposed that visceral adipose tissue growth is mainly due to hypertrophy, while in other locations there may be mainly growth through hyperplasia [89].
Impaired insulin-mediated antilipolysis and lactate release in adipose tissue of upper-body obese.
Horowitz JF, Klein S. Whole body and abdominal lipolytic sensitivity to epinephrine is suppressed in upper body obese women. Am J Physiol Endocrinol Metab. 2000; 278(6):E1144-E1152.