What does T:P stand for?
T:P stands for trough-to-peak ratios
This definition appears rarely
Samples in periodicals archive:
Data above are from seven placebo-controlled studies (2145 Benicar patients, 548 placebo patients). The blood pressure lowering effect was maintained throughout the 24-hour period with Benicar once daily, with trough-to-peak ratios.
For pure players, the average cost-income ratio has been 86. 5% since 2008, and this year has returned to an 88. 3% peak. This has meant that profitability amongst pure players has been squeezed. From trough to peak, cost-to-income ratios.
Once-daily administration of therapeutic doses of irbesartan gave peak effects at around 3–6 hours and, in one continuous ambulatory blood pressure monitoring study, again around 14 hours. This was seen with both once-daily and twice-daily dosing. Trough-to-peak ratios for systolic and diastolic response were generally between 60–70%. In a continuous ambulatory blood pressure monitoring study, once-daily dosing with 150 mg gave trough and mean 24-hour responses similar to those observed in patients receiving twice-daily dosing at the same total daily dose.
Peak (1 to 3 hours) effects were uniformly, but moderately, larger than trough effects with b. i. d. dosing, with the trough-to-peak ratio for diastolic blood pressure 65% to 80%. In the once-daily dose-response study, trough-to-peak responses of =50% were observed at some doses (including 1200 mg), suggesting attenuation of effect at the end of the dosing interval.