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What does TI-2 stand for?

TI-2 stands for thymus-independent type 2


This definition appears rarely

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Samples in periodicals archive:

Many studies have demonstrated that antibodies directed against the capsular polysaccharide are essential for protection against pneumococcal disease [25-27]. However, the native capsular polysaccharides are well-known thymus-independent type-2 (TI-2) antigens that lack T-helper epitopes and therefore mainly induce IgM antibodies, and to a lesser degree IgG [28]. The TI-2 characteristics of polysaccharides can be altered by conjugation of polysaccharide to a protein carrier (glycoconjugate) resulting in a switch to an anti-polysaccharide antibody response with characteristics of a T-cell-dependent response.