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Aust Fam Physician. 1976 May;5(4):550-9, 561. A screening test for thyroid function. Goodman E. The Achilles tendon reflex half relaxation time measurement (ART) has been used by many physicians both as a diagnostic test and for the assessment of progress in thyroid gland malfunction. Reference is made to some results obtained in Melbourne and in other countries using different methods of measurement of the ART for these purposes.
We describe a detailed approach to evaluating myo-mechanical properties in freshly explanted hindlimb muscle from the mouse. We describe the atraumatic harvest of mouse extensor digitorum longus muscle, mounting the muscle in a muscle strip myograph (Model 820MS; Danish Myo Technology), and the measurement of maximal twitch and tetanic tension, contraction time, and half-relaxation time.
Representative results for the contractile and passive properties of the EDL muscle. The contractile properties of the EDL muscle are characterized by the specific twitch force (A), the specific tetanic force (B), the time to peak tension (C) and the half relaxation time (D). The passive properties of the EDL muscle are assessed by the stress strain profile (E) and the SSR. *, mdx mice are significantly different from age-matched BL10 mice.
001) was accompanied by reduced passive twitch contraction and half relaxation time (Figure 2). Myoelectric alterations after voluntary induced high- and. by Tomazin, Katja; Sarabon, Nejc; Strojnik, Vojko / Journal of Sports Science and Medicine.
Other possible causes of functional loss include a deterioration of end-plate structures, impaired excitation-contraction coupling, and decreased fiber recruitment. Both contraction time and half-relaxation time are prolonged, and maximal contraction velocity is decreased. Changes are greater in the legs than in the arms, possibly because there is a greater decrease in use of the legs with aging.
Factorial analysis of the paired data revealed a main effect (p < 0. 05) of the co-overexpression of the native a- and ß-CaMKII isoforms on the contractile parameters time-to-peak-twitch force (-16%) and half-relaxation-time (-15%) for the combined data from SOL and GM muscle (Figure 2). In SOL muscle alone, a trend for a shortened half-relaxation-time was identified. Maximum twitch force and maximum tetanic force, and fatigability of tetanic force, did not differ between control- and a/ß CaMKII-transfected GM and SOL.