This definition appears rarely
2001; Jackson, 2001, 2002; Uematsu et al. , 2007). We examined whether NHEJ pathway is responsible for the repair of the DNA damage induced by Ag-np with regards to the status of DNA-PKcs in mammalian cells. Single-cell gel electrophoresis (also known as Comet assay) under alkaline condition (pH 13) was used to determine the DNA damage induced by Ag-np. DNA damage such as DSBs, single-strand breaks, and alkali labile sites.