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There are essentially two mechanisms by which resistance to nucleoside reverse transcriptase inhibitors (NRTIs) can occur. The first involves mutations (e.g., M184V...
Multiplication. After the virion enters the cell, viral reverse transcriptase transcribes the viral RNA into DNA, which integrates into the host cell genome.
Reverse Transcriptase Inhibitors: Non-Nucleoside Analogues. Brand Name. Generic Name. Dosage. Considerations and Adverse Effects