What does RPV stand for?
RPV stands for relative potency values
This definition appears rarely
See other definitions of RPV
Samples in periodicals archive:
Relative Potency Values Derived from Hepatic Vitamin A Reduction in Male and Female Sprague–Dawley Rats Following Subchronic Dietary Exposure to Individual Polychlorinated Dibenzo- p -dioxin and Dibenzofuran Congeners and a Mixture Thereof Fattore, Elena; Trossvik, Christina; Håkansson, Helen This study investigated the potency of individual polychlorinated dibenzo- p -dioxins (PCDDs) and dibenzofurans (PCDFs) to reduce hepatic vitamin A in the rat.
A more recent technical reference is CVB SOP ‘Estimating Relative Potency’ (CVBSOP0102. 01) dated March 14, 2014. BioTek’s Gen5™ software can be used to estimate relative potency values consistent with CVBSOP0102. 01. This Tech Note describes how to configure pre-defined Gen5 sample files to estimate relative potency values (Table 1). Sample files are compatible with Gen5 software versions 2.
The relative potency value is only relevant when the factor variable is statistically significant. The factor is significant when the p-value in the Regression table is less than your chosen alpha level, usually 0. 05. If the factor is not significant, then the confidence interval for relative potency will contain 1.
Since there are thousands of dioxin-like compounds (DLCs), one use of screening assays is to determine if all of the aryl hydrocarbon receptor (AhR) active DLCs in a mixture have been accounted for in instrumental analyses. For this purpose, bioassay-specific relative potency (ReP) values are needed. RePs of 21 polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls that exhibit effects mediated through the AhR were determined by use of the H4IIE-luc assay.