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Ion Selective Field Effect Transistors (ISFET) are novel integrated devices for micro electrochemical Lab-on-a-Chip systems. These are the most common types of ChemFETs (chemically sensitive field-effect transistors), where the structure is the same as that of a normal metal-oxide-semiconductor field-effect transistor (MOSFET) except for the transistor gate, which represents the sensitive area and incorporates the means of transduction from an ion concentration to a voltage.
The instability of the dc operating point in pH-sensitive ion-selective field effect transistors (ISFETs) renders the continuous monitoring of physiological pH using these devices inaccurate. This instability, commonly known as drift, manifests itself as a relatively slow, monotonic change in the measuring output signal in the absence of variations in the pH. In this work, a method for correction of ISFET drift is presented.
Commercially available solid state pH electrodes are mainly built around Ion Selective Field Effect Transistors.