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What does NCA90 stand for?

NCA90 stands for nonspecific cross-reacting antigen 90


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Hefta SA, Paxton RJ, Shively JE (1990). "Sequence and glycosylation site identity of two distinct glycoforms of nonspecific cross-reacting antigen as demonstrated by sequence analysis and fast atom bombardment mass spectrometry. ". J. Biol. Chem. 265 (15): 8618–26.
A total of 22 genes have been identified in the carcinoembryonic antigen (CEA) gene family. The protein products of this family are highly homologous and include CEA, biliary glycoprotein, nonspecific cross-reacting antigen 50/90 (NCA 50/90), NCA 95, and pregnancy-specific ß-glycoprotein. We used a monoclonal antibody with high affinity to develop a specific enzyme-linked immunosorbent assay (ELISA) method for NCA 50/90 in serum and plasma.
1994;54:1227-1234. Published online March 1, 1994. Cancer Res W. Jeffrey Allard, Irene E. Neaman, James J. Elting, et al. Patients with Breast, Lung, and Colon CancerNonspecific Cross-Reacting Antigen 50/90 Is Elevated in Updated Version http://cancerres. aacrjournals. org/content/54/5/1227Access the most recent version of this article at: Citing Articles http://cancerres. aacrjournals. org/content/54/5/1227#related-urlsThis article has been cited by 2 HighWire-hosted articles.
In the present study, we demonstrate that the antibody specifically recognized nonspecific cross-reacting antigen (NCA)-50/90 (CD66c), one of the carcinoembryonic antigen (CEA)-related glycoproteins encoded by a member of the CEA gene family. In addition, we show that the SA3544 antigen (NCA-50/90) was invariably expressed in cytoplasm of all of the human leukemic cell lines examined (sSA3544-positive B-lymphoid two, sSA3544-negative T or B-lymphoid and non-lymphoid 24) regardless of the presence or absence of surface expression of this antigen.
Abstract We have studied molecular heterogeneity of nonspecific cross-reacting antigen (NCA), a carcinoembryonic antigen (CEA)-related glycoprotein, in human granulocytes. NCAs of 80 and 58 kDa detectable by metabolic labeling (Kuroki, et al. , Jpn. J. Cancer Res. , 79, 82-90, 1988) were shown to be different molecular species from NCAs of 160, 95, 90 and 26 kDa identified by surface labeling with 125I, suggesting that there exist six different molecular species of NCA in granulocytes.