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What does LAF stand for?

LAF stands for lymphocyte-activating factors


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Interleukin-1 (IL-1), a polypeptide cytokine previously referred to as lymphocyte-activating factor, is predominantly produced and secreted by activated macrophages. It possesses a wide range of biologic functions and plays a role as an immune mediator. 132 At the level of the ovary, IL-1 suppresses the functional and morphologic luteinization of cultured murine and porcine granulosa cells. 133, 134 Exerted at physiologic concentrations (10-9 M), IL-1 action could not be attributed to altered cell viability.
The name "interleukin" was chosen in 1979, to replace the various different names used by different research groups to designate interleukin 1 (lymphocyte activating factor, mitogenic protein, T-cell replacing factor III, B-cell activating factor, B-cell differentiation factor, and "Heidikine"). This decision was taken during a meeting in Interlaken, Switzerland.