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What does JAF stand for?

JAF stands for juvenile aponeurotic fibroma


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Juvenile aponeurotic fibroma (JAF) and aggressive infantile fibromatosis (AIF) are considered PF when lesions are present on the sole of the foot. Like SF, JAF occurs most frequently in youths; the hard nodules grow slowly and adhere to deep structures. AIF is an exceptional condition that begins in an infant’s first year of life; it is the only PF with an invasive course, growing rapidly to pervade the tendons and muscles in the foot but fortunately does not spread to other parts of the body.
In juvenile aponeurotic fibroma, the cellular structures are oat-shaped. In the aggressive forms, there is an increase in mitotic activity and they are more cellular. The nodular lesions are hard, slow growing and adhere to the deep structures of the foot. Aggressive infantile fibromatosis appears within the first year of life. The lesion is a fast growing tumor that rapidly infiltrates the subcutaneous fat, aponeurosis and muscle.