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Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice
Intestinal epithelial cells (IECs) form a biochemical and physical barrier that maintains segregation between luminal microbial communities and the mucosal immune system.
The life cycle of an intestinal epithelial cell is terminated by apoptosis and/or cell shedding. Apoptotic deletion of epithelial cells from the intact intestinal...