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GAM protein, gp130-associated molecule Basic information More.
gp130-associated-molecule (GAM) is a recently cloned 24-kDa protein, which binds to gp130 at its cytoplasmic membrane-proximal region and has high homology with the N-terminal of Groucho/TLE molecules, a transcription co-repressor family playing an essential role in Notch signaling. Expression of GAM in COS7 cells inhibited the association of JAKs with gp130, and decreased the tyrosine phosphorylation level of these molecules as well.
Liu F, Liu Y, Jin B: Preparation and characterization of monoclonal antibodies against AES protein, a novel gp130 associated molecule.
FEI LIU, YIN LIU, BOQUAN JIN, BANG-QUAN DONG, YONG ZHU, Preparation and Characterization of Monoclonal Antibodies Against GAM Protein: A Novel gp130-Associated Molecule.
 Liu Y. Jin B. Q. Liu F. Cloning and eukaryotic expressing of a novel gp130 associated molecule.  Grimwood J. Gordon L. A. Olsen A. S.