What does G4D stand for?

The dense functional groups terminated on surface of dendrimers can react with intrinsic functional groups in protein-based scaffolds to form covalent binding. Conveniently in this way, scaffold stability can also be tailored by controlling the extent of cross-linking, which has the benefit of extending their in vivo life [123]. Availability of multiple functional groups effectively amplifies the number of sites available for conjugation with exogenous bioactive molecules. For example, Chan et al. [124] used generation 1 polyamidoamine (G1 PAMAM) dendrimer.

Ozturk, O. ; Black, T. ; Perrine, K. ; Pizzolato, K. ; Williams, C. T. ; Parsons, F. W. ; Ratliff, J. S. ; Gao, J. ; Murphy, C. J. , Xie, H. ; Ploehn, H. J. ; Chen, D. A. "Thermal Decomposition of Generation 4 Polyamidoamine Dendrimer Films: Decomposition Catalyzed by Dendrimer-Encapsulated Pt Nanoparticles," Langmuir 2005, 21, 3998-4006. doi: 10.