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What does M1 stand for?

M1 stands for first transmembrane domain


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Samples in periodicals archive:

The first transmembrane domain of the hepatitis B virus large envelope protein is crucial for infectivity. Lepère-Douard C1, Trotard M, Le Seyec J, Gripon P.
Citation: Wang J, Chen J, Enns CA, Mayinger P (2013) The First Transmembrane Domain of Lipid Phosphatase SAC1 Promotes Golgi Localization. PLoS ONE 8(8): e71112. doi:10. 1371/journal. pone.
Characterization of the cloned subunits has now shown that only two of the seven mammalian gene products have appreciable sensitivity to this analog (3). For this study, we sought to use chimeric P2X proteins to exploit the pharmacological differences between the aßmeATP-sensitive and -insensitive subunits in an effort to identify the domains and/or amino acid residues involved in determining agonist potencies at P2X subunits. Topological studies have shown that a P2X subunit has two transmembrane domains, with the intervening loop located extracellularly and the N and C termini located inside the cell (15). Previous studies from other groups have provided evidence that residues in the extracellular loop near the first transmembrane domain.