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What does F/C stand for?

F/C stands for filipin/cholesterol molar ratios


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Other Resources: Acronym Finder has 8 verified definitions for F/C

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and Bienvenue, A. (1988) Biochim. Biophys. Acta 939, 102–110), that is with filipin incorporated into membranes during their preparation. For preparations with filipin/cholesterol molar ratios of about 1:1 we confirm the results obtained by both methods. In the presence of an excess of filipin (filipin/cholesterol molar ratio 10:1), the CD spectrum observed with egg-yolk PC at 6°C (conditions used in the ESR study) is identical to that observed in the presence of pure DMPC above the transition temperature (Milhaud, J.
CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): desialylated transferrin sialyltransferase (ST) activities of rat liver Golgi apparatus are membrane-bound enzymes that can be released by treatment with Triton X-100. When protein substrates are used to assay these enzymes in freshly prepared Golgi vesicles, both activities are enhanced about eightfold by the addition of Triton X-100. When small molecular weight substrates are used, however, both activities are only enhanced about twofold by the addition of detergent. The enzymes remain inaccessible to large protein substrates even after freezing and storage of the Golgi preparation for 2 mo in liquid nitrogen. Accessibility to small molecular weight substrates increases significantly after such storage. GT and ST activities in Golgi vesicles are not destroyed by treatment with trypsin, but are destroyed by this treatment if the vesicles are first disrupted with Triton X-100. Treatment of Golgi vesicles with low levels of filipin, a polyene antibiotic known to complex with cholesterol in biological membranes, also results in enhanced trypsin susceptibility of both glycosyltransferases. Maximum destruction of the glycosyItransferase activities by trypsin is obtained at filipin to total cholesterol weight ratios of-1.6 or molar ratios of-1. This level of filipin does not solubilize the enzymes but causes both puckering of Golgi membranes visible by electron microscopy and disruption of the Golgi vesicles as measured by release of serum albumin. When isolated Golgi apparatus is fixed with