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What does CaN stand for?

CaN stands for constitutively activate calcineurin

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As a calcium-activated phosphatase, calcineurin is abundantly expressed in the heart and plays pivotal roles in many cardiovascular diseases involving oxidative stress. 26, 39, 40 It is still unknown whether calcineurin delivers pro-survival or pro-death signals in the heart. Transgenic mice that constitutively activate calcineurin.