What does BRB stand for?
BRB stands for blood-retina barrier
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Samples in periodicals archive:
These junctions restrict the diffusion of small particles between cells and compose the blood-retina barrier in their role in retinal endothelial cells and the blood-ocular barrier in their role in retinal pigment epithelium and ciliary body epithelium. The intercellular space at a zonula occludens is 2. 5 to 5 nm wide. The macula adherens junction, or desmosome, is a structural junction that resists shearing forces between cells.
The RPE is a layer of tight junction pigment cells that forms the outer blood-retina barrier. It serves a critical function in its role as the scavenger of decaying photoreceptor debris and waste disposal system for the retina. The pigment of the RPE also functions as a filter during angiography, obscuring the more posteriorly located choroid, choriocapillaris, and sclera (Figure 1-6).
In an effort to reduce absorption of low-wavelength visible light and retard its damaging effects, yellow-tinted, blue light-filtering (“blue-blocking”) intraocular lens implants have been developed. While there remains no prospective, randomized clinical trial proving any protection against AMD, the use of a blue-blocking IOL is defensible on the basis of its biological plausibility and may offer significant health care savings longterm given the increasingly aging population. 7 Despite concerns of diminished scotopic sensitivity and difficulties with color perception and brightness, visual function has been shown to be virtually identical in patients with yellow-tinted and standard IOLs. 8 Inflammation is known to incite cystoid macular edema, but may also contribute to the progression of AMD. Preoperative treatment with topical non-steroidal anti-inflammatory drugs (NSAIDs) has been shown to stabilize the blood-retina barrier.
the retinal blood vessel endothelial cells are joined by tight junctions which prevent leakage of fluorescein into the retina. This constitutes the blood retina barrier.
The two synaptic layers where visual signals must synapse as they emerge from the rods and cones on their way to the optic nerve are the two molecular layers (5 and 7) (Fig. R9). The blood supply to the retina is composed of the capillaries from the central retinal artery, which supply the inner two-thirds of the retina up to the outer plexiform layer, and the choriocapillaris, which supplies the outer one-third. There is no retinal circulation in the foveola (avascular zone). A blood-retina barrier.
It is a more powerful than beta-carotene, lutein, lycopene and vitamin E and most other antioxidants. It freely crosses the blood-brain and blood-retina barriers.