What does D2 stand for?
D2 stands for Type 2 iodothyronine deiodinase
This definition appears rarely
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Samples in periodicals archive:
Moreno M, Berry MJ, Horst C, Thoma R, Goglia F, Harney JW, Larsen PR, Visser TJ (May 1994). "Activation and inactivation of thyroid hormone by type I iodothyronine deiodinase". FEBS Lett. 344 (2-3): 143–6. doi:10. 1016/0014-5793(94)00365-3. PMID 8187873.
Imai Y, Toyoda N, Maeda A, et al. (2002). "Type 2 iodothyronine deiodinase expression is upregulated by the protein kinase A-dependent pathway and is downregulated by the protein kinase C-dependent pathway in cultured human thyroid cells". Thyroid 11 (10): 899–907. doi:10. 1089/105072501753210957. PMID 11716036.
The data suggest that IOP decreases cutaneous cell proliferation by inhibition of intracellular T(4) to T(3) conversion. The data provide indirect evidence of the presence of type 1 or type 2 iodothyronine deiodinase activity in skin cells. The data support our previous hypothesis that T(3) is necessary for normal cutaneous proliferation.
Roberts, SC; Bianco, AC; Stapleton, HM, Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers. , Chemical Research in Toxicology, vol 28 no. 6 (2015), pp. 1265-1274 [10. 1021/acs. chemrestox.