What does T/M stand for?
T/M stands for Tumor-to-muscle ratio
This definition appears rarely
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PET imaging and biodistribution studies were carried out in mice bearing both B1R-positive (B1R(+)) HEK293T::hB1R and B1R-negative (B1R(-)) HEK293T tumors. Both tracers cleared rapidly from most organs/tissues, mainly through the renal pathway. High uptake in B1R(+) tumors ((18)F-AmBF3-B9858: 3. 94 ± 1. 24% ID/g, tumor-to-muscle ratio 21. 3 ± 4. 33; (18)F-AmBF3-B9958: 4. 20 ± 0. 98% ID/g, tumor-to-muscle ratio 48.
Microvascular invasion (MVI) and poor differentiation are strong risk factors for recurrence, but these cannot be known preoperatively. The aim of this study was to investigate the correlation of 18F-FDG PET with MVI and differentiation, and predictive role of tumor-to-background ratio of PET for recurrence in HCC. METHODOLOGY: Fifty-four patients had 18F-FDG PET/CT study before surgical resection as a first treatment of HCC between December 2008 and December 2012. We analyzed the predictive role of metabolic parameters of PET for recurrence of HCC. Maximal standardized uptake value, tumor-to-nontumor ratio, tumor-to-muscle ratio.
5). After 1 h post intravenous injection of BODIPY-BBN 5, ex vivo fluorescent imaging of tumor and muscle revealed uptake of the imaging agent in the tumor with GRP receptor overexpression (Fig. 5a). Analog to this finding, the intensity of specific fluorescent signal of the imaging agent yielded a tumor to muscle ratio of 5. 7 (Additional file 1: Figure S4). Control mice, injected with PBS (n = 3), did not show fluorescence in their tumor tissue, yielding a tumor to muscle ratio of 0.
8±0. 2 %ID/g, respectively) than the free peptide (64)Cu-DOTA-TATE (1. 4±0. 3 %ID/g) 24h post-injection. Importantly, (64)Cu-loaded PEGylated liposomes with TATE showed significantly higher tumor-to-muscle (T/M) ratio (12. 7±1. 0) than the control-liposomes without TATE (8. 9±0. 9) and the (64)Cu-DOTA-TATE free peptide (7. 2±0.