What does T-APC stand for?
T-APC stands for T-cell antigen-presenting cell
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38% 8. 176 2 - Template:Namespace_detect --> Retrieved from "https://en. wikipedia. org/w/index. php?title=Antigen-presenting_cell&oldid=685366440" Categories: Defensive cells Antigen presenting cells.
Looking for online definition of antigen-presenting cell in the Medical Dictionary? antigen-presenting cell explanation free. What is antigen-presenting cell? Meaning of antigen-presenting cell medical term. What does antigen-presenting cell mean?
Comparison of microglia and infiltrating CD11c+ cells as antigen presenting cells for T cell proliferation and cytokine response Agnieszka Wlodarczyk, Morten Løbner, Oriane Cédile and Trevor Owens*.
Thus, aAPC represent a robust versatile technology useful for inducing and expanding NKT cells. The generation of aAPCs takes less than one week and is suitable for the production of large quantities of beads. However, a critical step in generating the aAPC is to confirm that CD1d-Ig is stably immobilized on the surface of the beads and to assess their functionality to ensure consistency from batch to batch. A potential limitation of the system is that there is not a mechanism in place to turn off stimulation, other than mechanical removal of the beads. Specifically, the engagement of the T cell receptor (TCR) with the antigen: CD1d/MHC complex typically generate the immunological synapse in concert with accessory/adhesion molecules, which can result in the induction of inhibitory or suppressive factors on both the T cell and antigen presenting cell.
Each T cell expresses clonal TCRs which recognize specific peptide/MHC complex during physical contact between T cell and antigen-presenting cell-APC (MHC class II) or any other cell type (MHC class I)  High on-rate and off-rate is characteristic for TCR and peptide/MHC interaction at physiological temperature. TCRs have very high degree of antigen specificity, despite of fact that the affinity to the peptide/MHC ligand is in the micromolar range.