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Hits numbers of genes involved in the relevant methanogenesis pathways in anaerobic digestion. The three known pathways involved in methanogenesis are colored differentially. The acetoclastic pathway is shown in red, the hydrogenotrophic pathway is marked in green, and the methylotrophic pathway is presented in green. FdhA, glutathione-independent formaldehyde dehydrogenase; EchA, hydrogenase subunit A; FmdA, formylmethanofuran dehydrogenase subunit A; FTR, formylmethanofuran-tetrahydromethanopterin N-formyltransferase; MCH, methenyltetrahydromethanopterin cyclohydrolase.