What does M-R stand for?
M-R stands for M-cholinergic receptor
This definition appears rarely
Samples in periodicals archive:
50. Shi R, He L, Hu Y, et al. The regulatory action of radix astragali on M-cholinergic receptor of the brain of senile rats. J Tradit Chin Med 2001;21:p. 232-235.
Two types of pharmacologic receptors transmit the influence of the parasympathetic and motor divisions of the nervous system (through the mediator acetylcholine): The N-cholinergic receptors transmit nerve impulses to the skeletal muscles and from neuron to neuron within the nerve ganglia, while the M-cholinergic receptors help regulate cardiac activity and the tone of smooth muscles. The influence of the sympathetic nervous system (through the mediator norepinephrine) and of the hormone secreted by the adrenal medulla (epinephrine) is transmitted by the α- and β-adrenergic receptors.
They also increase phagocytosis and demonstrate hepatoprotective effects on chemically-induced liver injury in vitro (6) and in vivo (4). Studies conducted in China suggest that astragalus, when used with Angelica sinsensis, exerts reno protective effects by mediating gene expression. Astragaloside IV, a saponin, increases tissue-type plasminogen activator (t-PA) synthesis and downregulates the expression of plasminogen activator inhibitor type 1 (PAI-1) (21). In IgA nephropathy patients, Astragalus injection decreases Cosmc gene expression and increases IgA1 O-glycosylation level (26). Astragalus also increases M-cholinergic receptor.
50. Shi R, He L, Hu Y, et al. The regulatory action of radix astragali on M-cholinergic receptor of the brain of senile rats. J Tradit Chin Med 2001;21:p. 232-5.