What does LAD stand for?
LAD stands for Leukocyte Adhesion Deficiency-1
This definition appears rarely
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Samples in periodicals archive:
bovine leukocyte adhesion deficiency lethal hematological defect inherited as a recessive trait in Holstein cattle; characterized by poor growth, recurrent infection and poor responsivity to standard treatments in calves from 2 to 8 weeks of age. Profound neutrophilia. Death supervenes before two years of age. Called also BLAD.
leukocyte adhesion deficiency (LAD) an autosomal inherited disorder caused by a defective integrin molecule (CD18) that is important for cellular adhesion. This defect causes neutrophils to be immotile and unable to phagocytose. Patients with LAD have recurring bacterial infections and impaired wound healing, which may lead to necrosis and gangrene.
She is an active member of the Critical Care, CPR and MICU leadership/QI committees. Dr. Harris is involved with basic science and translational research as an active member of the Vascular Biology Laboratory headed by Drs. Andy Weyrich and Guy Zimmerman. Over the last five years she has published on research topics including; tissue factor mRNA expression in platelets isolated from septic patients, the characterization of the molecular defect in an Leukocyte Adhesion Deficiency.