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What does L-PIA stand for?

L-PIA stands for L-N6-(2-phenyl-isopropyl)adenosine


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Briefly, epididymal fat tissue was minced and digested in a Krebs-Ringer bicarbonate (KRB) buffer (pH 7. 4) supplemented with 3% fatty acid–free BSA fraction V, 0. 5 mmol/L adenosine, and 1 mg/mL type I collagenase. After 40-min digestion and three washes, isolated adipocytes were resuspended in KRB supplemented with 5 mmol/L glucose and 3% fatty acid–free BSA. Suspended adipocytes (∼6,000 cells) were used for a lipolysis assay in 400 μL KRB buffer plus 3% fatty acid–free BSA, 1 unit/mL adenosine deaminase, and 100 nmol/L (-)-N6-(2-phenyl-isopropyl)-adenosine.
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Sigma-Aldrich offers Sigma-P4532, (−)-N6-(2-Phenylisopropyl)adenosine for your research needs. Find product specific information including CAS, MSDS, protocols and references.
Spinal R-phenyl-isopropyl adenosine inhibits spinal dorsal horn neurons responding to noxious heat stimulation in the absence and presence of sensitization. Sumida T1, Smith MA, Maehara Y, Collins JG, Kitahata LM.
v. ) and intraperitoneal (i. p. ) injection in conscious mice. The compounds tested were the non-selective adenosine receptor agonist 5'-N-ethyl-carboxamidoadenosine (NECA), the adenosine A1 receptor-selective agonists cyclopentyl-adenosine (CPA), N6-(9R-phenyl-isopropyl)-adenosine.