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The next interesting compound from this group is a synthetic homologue of L-NIO N6-(1-iminoethyl)-L-lysine (L-NIL), which was developed in the nineties. It is a moderately selective inhibitor of iNOS and has not been found to cause NOS inactivation (Table 1). This compound has similar chemical properties to L-NIO . Later, a more stable and less hygroscopic prodrug of L-NIO, N6-(1-iminoethyl)-L-lysine 5-tetrazole-amide (L-NIL-TA, also referred to as SC-51), was introduced.