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What does G-CSF stand for?

G-CSF stands for IL-3)/granulocyte colony-stimulating factor

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Granulocyte macrophage colony-stimulating factor receptor From Wikipedia, the free encyclopedia Jump to: navigation, search Colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 3CXE Identifiers Symbols CSF2RA ; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMR; SMDP4 External IDs OMIM: 425000 MGI: 1339754 HomoloGene: 48406 ChEMBL: 2020 GeneCards: CSF2RA Gene Gene ontology Molecular function • receptor activity • granulocyte colony-stimulating factor.
ISRAEL : Teva Announces Data on Granulocyte Colony Stimulating Factor.
Granulocyte-macrophage colony-stimulating factor (GM-CSF), as its name suggests, sends cells down the path leading to both those cell types. In due course, one path or the other is taken. Under the influence of granulocyte colony-stimulating factor (G-CSF), they differentiate into neutrophils. Further stimulated by interleukin-5 (IL-5) they develop into eosinophils.
Several pharmacological strategies for neuroprotection such as counteracting excitotoxicity by blocking NMDA (N-methyl-D-aspartate-) or α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid-type glutamate receptors have clinically failed, partly because of dose-limiting side effects in the central nervous system (CNS). Exploitation of an endogenous neuroprotective system for therapy is potentially advantageous to this approach, as the existence of such mechanisms points to molecular events in the ischemic pathophysiological cascades that can be interfered with without disturbing essential systems of the CNS. Among the clinically interesting candidates for endogenous neuroprotectants, two proteins are considered particularly promising for a number of reasons: erythropoietin (EPO) (for review see Hasselblatt et al, 2006) and granulocyte colony-stimulating factor.