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What does BCCP stand for?

BCCP stands for Biotin Carboxy Carrier Protein


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It covalently attaches to the epsilon-amino group of specific lysine residues in these carboxylases. This biotinylation reaction requires ATP and is catalyzed by holocarboxylase synthetase. [15] In bacteria, biotin is attached to biotin carboxyl carrier protein (BCCP) by biotin protein ligase (BirA in E. coli). [16] The attachment of biotin to various chemical sites, biotinylation, is used as an important laboratory technique to study various processes, including protein localization, protein interactions, DNA transcription, and replication.
Like the other biotin-dependent carboxylating enzymes in mammals, PC is multifunctional and contains three distinct enzymatic domains: the biotin carboxylase (BC) domain, the carboxyltransferase (CT) domain, and the biotin carboxyl carrier protein (BCCP) domain. PC is composed of four identical subunits generating an α4 homotetrameric enzyme. The human PC gene is located on chromosome 11q13.