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What does PAC stand for?

PAC stands for BAC)/P1-derived artificial chromosome


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They may be as small as a few hundred base pairs, up to several Mbp, entire chromosomes, or even entire genomes. Larger probes usually are not "unique" in their sequence but contain disperse repetitive elements that have to be suppressed to avoid unspecific hybridization patterns (suppression hybridization, see below). PCR products or cDNAs can be mapped on metaphase chromosomes, however, since they are rather short there is quite a workload to visualize these sequences. Widely used probes for physical mapping by FISH are genomic DNA sequences cloned in vectors such as Cosmids, P1 derived artificial chromosomes.
The use of high-capacity yeast, bacteria and P1-derived artificial chromosomes (respectively YACs, BACs, and PACs) allows a different route to human artificial chromosomes (HAC) construction, because artificial chromosomes could be prepared as complete vectors before transfection into mammalian cells. Ikeno et al. in 1998 cloned α-satellite DNA into a YAC vector and replaced its left and right arms with sequences containing human telomeres and selection marker genes for mammalian cells.
Institute of Human Genetics and Anthropology, University of Freiburg, Germany. For a long time, the evolutionary relationship between human and African apes, the 'trichotomy problem', has been debated with strong differences in opinion and interpretation. Statistical analyses of different molecular DNA data sets have been carried out and have primarily supported a Homo-Pan clade. An alternative way to address this question is by the comparison of evolutionarily relevant chromosomal breakpoints. Here, we made use of a P1-derived artificial chromosome.
coli, we have developed a system that has high and accurate efficiency in the selection of a well-proven homologous recombination event induced by specific genes of the λ-prophage. This system should be applicable to plasmids, P1-derived artificial chromosomes or bacterial artificial chromosomes. In theory, this system can allow unlimited seamless modifications in different regions of the vectors or chromosomes concerned.
u. MAAL MAAP Macroevolution Macrorestriction map Map Unit Mapping Marker Maternal inheritance Mating Mating frequency Mating system Mating type Matroclinous inheritance Mb Megabase Meiosis Meme Mendel Mendel's first law Mendel's second law Messenger RNA Metacentric Metaphase Methylation Microsatellite Migration Minisatellite Mispairing Mitochondria mitochondrial DNA Mitosis Monoclonal Monoecious Monogenic Monohybrid cross Monosom Mosaicism Motif mRNA mtDNA Multifactorial disorder Multigenic disorder Multiple allelism Multiple arbitrary amplicon profiling Multiplexing Mutation Mutator mutation Natural selection Negative interference Neo-darwinism Nick translation Nitrogenous base Nondisjunction Non-linkage Nonsense mutation Northern blotting Nuclease Nucleic acid Nucleolus Nucleoside Nucleosome Nucleotide Nucleus Offspring Oligonucleotide Oncogene Ontogeny Open reading frame Operator Operon Order ORF Origin Orthology Outbreeding Overlapping clones Ovum P1-derived artificial chromosome.