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Anti-transglutaminase antibodies (ATA) are autoantibodies against the transglutaminase protein. Antibodies serve an important role in the immune system by detecting cells and substances that the rest of the immune system then eliminates. These cells and substance can be foreign (for example, viruses) and also can be produced by the body (for example, cancer cells). Antibodies against the body's own products are called autoantibodies.
Research from JAMA Neurology — Transglutaminase 6 Antibodies in the Serum of Patients With Amyotrophic Lateral Sclerosis