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What does AB+ stand for?

AB+ stands for Alcian blue-positive


This definition appears rarely

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Endoscopically, there must be columnar epithelium within the esophagus. Histologically, the epithelium must be metaplastic, as defined by the presence of goblet cells. An Alcian blue stain at pH 2. 5 stains the acidic mucin present in the goblet cells. The most common errors in the identification of goblet cells are: 1) "pseudogoblet" cells; and 2) Alcian blue positive.
(A) Knee joint samples were harvested 4, 8, 12, or 16 weeks post-surgery and Alcian blue/Hematoxylin/Orange G staining was performed. Histological results showed decreased articular cartilage degradation in Mmp13Col2ER mice 8, 12 and 16 weeks post-surgery. (B) Histological grading by blinded observers confirmed decreased articular cartilage degradation in Mmp13Col2ER mice at 8, 12, and 16 weeks compared to control Cre-negative mice (*P < 0. 05). (C) Tibia articular cartilage area was quantified by tracing the Alcian blue-positive.
Alcian blue staining at day 15 showed that the CPCs began producing proteoglycans earlier than did the pellet culture transplants (Supplemental Figure 5A, upper panel), suggesting that they were efficiently induced to undergo chondrogenic differentiation. At day 30, the vascularized transplants were strongly positive for proteoglycans (Supplemental Figure 5A, middle panel). At day 60, terminally differentiated mature chondrocytes were distributed homogenously in the majority of the transplants in which progenitors were transplanted along with endothelial cells (Figure 5B, left). In contrast, a much smaller proportion of the pellet transplants, which lacked endothelial cells, were positive for proteoglycans at days 15, 30, and 60 (Figure 5B, right). Quantification of the Alcian blue–positive.
In order to accurately identify the alcian blue positive specialized IM without histological study, the technique of methylene blue chromoendoscopy must be used [5, 6]. Methylene blue dye is absorbed by the metaplastic columnar epithelium cells, with the greatest concentration being in the acid mucopolysaccharide of the goblet cell. False positive staining must be avoided by meticulous removal of surface mucus (which stains strongly positive by methylene blue) by application of 10% acetyl cysteine (Mucomyst) and copious flushing of the surface with water (Canto).
Surgical resection of the involved lobe was performed. Both cysts showed fibrous, calcified walls and contained yellowish mucinous material (Figure 3,4) The smaller cyst was unilocular without any epithelial lining and showed a foreign body-type giant cell reaction in the wall. The larger cyst was multilocular and was partially lined by simple columnar mucinous epithelium (Figure 5a) which in several areas assumed different degrees of malignancy, with nuclear atypias, multilayering and increased mitotic activity (Figure 5b). Extensive and careful sampling revealed foci of malignant, infiltrating glands (Figure 6a), necrosis and foci of bone metaplasia (Figure 6b). Alcian Pas staining showed the presence of Alcian blue positive.
(a) Control, (b) radon inhalation only, (c) sham inhalation with DSS administration, and (d) radon inhalation with DSS administration. All samples were stained with alcian blue. Arrow indicates alcian blue-positive goblet cells. Scale bar is 100 µm (