What does FAB stand for?
FAB stands for AML-French-American-British
This definition appears rarely
See other definitions of FAB
Samples in periodicals archive:
(French-American-British) a classification of acute leukemia produced by a three-nation joint collaboration; acute lymphoblastic leukemia is subdivided into three types and acute myelogenous leukemia is subdivided into eight types. French-American-British (FAB) classification of acute leukemias: the myeloid leukemias are divided into eight types (M0-7) and the lymphoblastic leukemias into three (L1-3).
We report two cases of trisomy 4 with double minute chromosomes (dmin): one in a woman with acute myeloid leukemia (AML), French-American-British subtype M2, the other in a man with chronic myelomonocytic leukemia. In the former case, many cells without trisomy 4 but with dmin were present, a finding not observed in previously reported cases. In both cases, fluorescence in situ hybridization studies demonstrated the double minutes to be MYC amplicons.
1-15 As a consequence of the ever more frequent description of these cases, the members of the French-American-British (FAB) group permanently included this particular variant of myeloid leukemia into the FAB classification. 16 They categorized this leukemia as AML-M0 and established strict morphological, cytochemical, and phenotypic criteria based on which diagnosis could be made. 16 By definition, the diagnosis of AML-M0 requires less than 3% MPO+ and/or SBB+ blasts, expression of myeloid-associated markers, and lack of B/T-lineage–associated antigens.