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Fabbri et al (1991) Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536). J. Enzyme Inhib. 5 87. PMID: 1669444.
as well as a simultaneous activation of extracellular signal-regulated kinase (ERK) (Fig. 4b and Supplementary Fig. S10)43, 44, 45. Of note, both of these events were cAMP-dependent (Fig. 4c–e); hence, the pharmacological inhibition of cAMP synthesis in vivo with 9-(tetrahydro-2-furyl)-adenine.