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The key step in the biosynthesis of cholesterol is the conversion of 3-hydroxy-3-methyl-glutaryl-Coenzyme A to mevalonate by HMG CoA reductase. This is the rate limiting step in cholesterol biosynthesis.
HMG-CoA Reductase Inhibitor Aka: HMG-CoA Reductase Inhibitor, 3-Hydroxy-3-Methyl-Glutaryl Coenzyme.
A considerable amount of researches on the possible extrathyroidal effects of TSH has been published. For example, positive associations between the TSH level and waist circumference, body mass index and blood pressure have been described [10-12]. Regarding lipid metabolism, our previous study  indicated that TSH might up-regulate hepatic 3-hydroxy-3-methyl-glutaryl coenzyme.