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The combined action of certain mutagenic substances on the hereditary structures of barley. Communication I. Action of 8-ethoxycaffeine and 1,4-bis-diazoacetylbutane.
A selective effect of 1,4-bis-diazoacetylbutane (DAB) with respect to individual genes is observed when studying its mutagenic action on bacterial strains. Escherichia coli and Salmonella typhimurium. The frequency of mutations to thr+ exceeded in three orders the background of spontaneous variability for this marker. No induced mutations to trp+ and his+ leu+, which might be the result of transition, transversions, suppressor mutations and frame shift mutations, were detected.
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