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What does F18-FDG stand for?

F18-FDG stands for fluorine-18-2-fluoro-2-deoxy-D-glucose

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Bone scans are most commonly used for detection of osseous involvement in systemic processes (e. g. , metastatic disease) and may result in false-positive diagnosis of malignancy in a patient with rib fractures, although the pattern of tracer uptake can often help differentiate the 2 processes. Bone scans have limited use in distinguishing acute and subacute/chronic rib fractures as they will usually be positive within 24 hours after an injury, but the return to normal can be slow (79% by 1 year, 93% by 2 years, and 100% in 3 years). Furthermore, patients with known malignancy and benign rib fractures may exhibit false-positive findings on fluorine-18-2-fluoro-2-deoxy-D-glucose.
According to one study, "It has a high PPV and can be used for problem-solving in patients with indeterminate findings on conventional imaging. " Another review stated that for bladder cancer fluorine-18-2-fluoro-2-deoxy-D-glucose PET (FDG-PET) is useful for identifying distant metastases but is limited for detecting primary tumors due to the urinary excretion of FDG. The role of 11C-choline and 11C-methionine, the authors added, remains to be evaluated further in clinical studies.